Lipedema is a chronic condition characterized by the abnormal and painful accumulation of fatty tissue, typically seen on the legs and buttocks. More common in women, this condition, unlike cellulite, is a medical condition and can become progressive and detrimental to quality of life if left untreated. In lipedema, the fatty tissue causes tenderness and pain to the touch, and irregular, nodular structures can form under the skin. This article provides comprehensive information on the symptoms, causes, diagnostic methods, and treatment options for lipedema.
Lipedema is a chronic condition characterized by abnormal fat accumulation, usually in the lower body, particularly in the legs and buttocks. The most characteristic symptoms of this condition are:
Symmetrical and excessive fat accumulation: Lipedema occurs symmetrically in both legs, with fatty tissue concentrated particularly around the hips, thighs, and knees.
Tenderness and pain to touch: Pain, tenderness, and sensitivity to touch are frequently experienced in the affected areas.
Irregular masses under the skin: Nodular structures or lumps may be felt beneath the fatty tissue.
Swelling in the arms and legs: Significant swelling may occur in the affected areas, especially at the end of the day or after prolonged standing.
Easy bruising: Bruises and bruises occur more easily than normal.
Limited movement and a feeling of heaviness: Feelings of heaviness and difficulty moving in the legs are common.
Lipedema symptoms often appear or worsen during periods of hormonal fluctuation, such as puberty, pregnancy, or menopause. Early diagnosis and appropriate treatment are crucial to prevent the disease from progressing.
Lipedema treatment is planned according to the disease’s stage, severity, and impact on a person’s quality of life. While there is no definitive “cure” treatment yet, it is possible to alleviate symptoms and halt progression. Treatment generally consists of conservative (non-surgical) and surgical methods:
Circulation is supported and edema is reduced by using special medical stockings or bandages.
Lymph flow is encouraged with special massage techniques applied by experts.
Low-impact exercises (swimming, walking, Pilates) increase circulation and relieve symptoms.
Disease management is supported with weight management and anti-inflammatory nutrition plans.
Psychological support may be recommended to cope with chronic pain and body image.
In advanced cases, fat deposits can be removed using specialized techniques such as tumescent liposuction. This procedure:
Provides permanent reduction of fatty tissue.
Helps reduce pain and mobility limitations.
Can significantly improve the patient’s quality of life.
However, liposuction must be performed by a surgeon experienced in lipedema, and supportive treatments such as compression and physiotherapy should be continued after surgery.
Ultimately, treating lipedema requires a multidisciplinary approach. Early diagnosis, appropriate treatment, and lifestyle changes can slow disease progression and significantly reduce pain and discomfort.
Although the exact cause of lipedema is unknown, experts believe multiple factors contribute to the development of this condition. The most widely accepted views are as follows:
Lipedema often appears or worsens during periods of hormonal change, such as puberty, pregnancy, birth control use, and menopause. This suggests that the condition may be related to female hormones such as estrogen. Therefore, lipedema occurs almost exclusively in women.
A significant number of patients with lipedema have family members with similar symptoms. This suggests that the disease may be hereditary. Some research suggests that hormonal changes may trigger lipedema in individuals with a genetic predisposition.
Although the lymphatic system is not directly affected by lipedema, it can occur alongside lymphedema in later stages of the disease. The pressure on the circulatory system and the expansion of fatty tissue can also negatively impact lymph flow.
Obesity isn’t the cause of lipedema, but excess weight can worsen symptoms. Even if people with lipedema lose weight, the abnormal fat tissue usually persists and accumulates symmetrically in the legs and buttocks.
Lipedema is a systemic disorder of adipose tissue that results from the interaction of genetic and hormonal factors. Early diagnosis is crucial for maintaining quality of life and preventing disease progression.
Lipedema most commonly affects the lower extremities (legs) symmetrically, but it can also affect the arms. The most commonly affected areas are:
Buttocks and thighs (inner and outer sides)
Around the knees (especially the inner sides)
Calves
Areas extending down to the ankles – feet are usually not affected (this is known as the “cuff sign”)
Upper arms (especially the triceps area)
Less common: The abdomen, sides of the back (love handle area), and upper trunk can be affected, but this is much less common than the legs and arms.
Classic Type Distribution
Type I: Buttocks and upper thighs (riding breeches appearance)
Type II: Buttocks to the knees
Type III: Buttocks to the ankles (feet intact)
Type IV: Involvement of the arms
Type V: Involvement focused on the calves
Note: In lipedema, the hands and feet are usually spared. If the disease progresses and lipo-lymphedema develops, swelling may also spread to the hands and feet.
Lipedema is usually diagnosed based on clinical examination and the patient’s medical history. Currently, there is no specific laboratory test or imaging method for lipedema. Therefore, the diagnosis must be carefully evaluated by a specialist.
1. Medical History (Anamnesis):
The physician will inquire about the patient’s complaints, the onset of symptoms, and any family history of similar conditions. An increase in symptoms during periods of hormonal fluctuation is important for diagnosis.
2. Physical Examination:
The physician will assess the distribution of fat. Lipedema is often characterized by:
Symmetrical fat accumulation in the legs,
Unaffected feet (cuff sign),
Tenderness and pain to touch,
Subcutaneous nodules (lumps).
3. Imaging Methods (If Necessary):
Can be used to support the diagnosis and exclude other conditions:
Doppler Ultrasound: Used to rule out conditions such as venous insufficiency or lymphedema.
MRI or USG: Can provide information about the structure of subcutaneous fat tissue, but is generally not necessary.
4. Differential Diagnosis:
Lipedema is often confused with conditions such as obesity, cellulite, lymphedema, and venous insufficiency. Therefore, evaluation by an experienced specialist is critical for accurate diagnosis.
Conclusion:
Lipedema is diagnosed based on a detailed physical examination and the patient’s history. Early diagnosis is crucial for halting disease progression and improving quality of life. If the diagnosis is in doubt, consulting a Physical Medicine and Rehabilitation or Vascular Surgery specialist is the best course of action.
The doctor you should consult for the diagnosis and treatment of lipedema may vary depending on the severity of the condition and symptoms. However, in general, the specialist areas of Plastic, Reconstructive, and Aesthetic Surgery are the most appropriate for lipedema:
In advanced stages of lipedema, doctors in this field are consulted for surgical treatment methods such as liposuction. It is important to choose a surgeon with experience in lipedema.
Lipedema surgery (liposuction) can reduce the long-term effects of the condition, but it does not completely eliminate it. Lifestyle changes and compression support should continue after surgery.
No. Lipedema is different from normal fat accumulation. While weight can be lost throughout the body with diet and exercise, the fat in areas with lipedema remains largely stable.
Yes. Lipedema can worsen over time, increasing pain and decreasing mobility. Early conservative treatment can prevent future complications.
It’s very rare. Lipedema occurs in 99% of women. Similar fat distribution seen in men is usually associated with other causes.
Answer:
Stage 1: The skin surface is smooth, soft-textured, but sensitive.
Stage 2: Irregular, nodular structures are felt under the skin.
Stage 3: Fatty tissue hardens, and deformities occur.
Stage 4 (Lipo-lymphedema): Lymphedema accompanies lipedema.
No. Lipedema usually occurs during hormonal transitions such as puberty, pregnancy, and menopause. However, there may be a genetic predisposition.
Yes. Because capillaries weaken in areas with lipedema, bruises (bruises) occur easily, sometimes even unnoticed.